ART – Assisted Reproduction Techniques – Recent trends

Assisted Reproductive Techniques

           The present scenario of conception shows at least 10-15% of the couples suffering intricacy in conceiving a baby, worldwide as per WHO.

            Prevalence of Infertility is in ascending trend, due to transformation of our life style, abundant changes in the environment as an outcome of industrialization, urbanization, vehicles pollution and other occupational hazards. Insecticides, pesticides, drugs and chemicals also contribute a greater role to this increasing trend. 

            AssistedReproductive Techniques – commonly known as Test tube baby treatment is an advanced scientific treatment, in which wife’s eggs are fertilized with husband’s sperms, outside the body in an ideal laboratory environment. They are meticulously handled and cultured using incubators and very many updated gadgets. If the resultant embryos are replaced into the wife’s uterus on fifth day which is called Blastocyst transfer, it gives an incredible success rate of 60-70%, on the contrary to the commonly performed second or third day uterine transfer which offers, just 20-30% success rates only. Blastocyst culture is the routine culture method in our laboratory since 2000 at Genesis Fertility Centre –GFRC – (a unit of Maaruthi Medical Centre and Hospitals) Erode.

MMCH Hospital, Erode. Tamilnadu. India.

        In severe Male Infertility with very low sperm counts, we adopt a treatment modality called ICSI- Intra Cytoplasmic Sperm Injection. In this, one healthy sperm is enough for one retrieved egg, which is aspirated in a micro needle and injected into the cytoplasm of the egg under higher magnification, resulting in a chromosomally normal embryo with enhanced growth and implantation potency. We add an advanced technology called Laser assisted hatching before embryo transfer, which sharply rises the opportunities for successful pregnancies. We are doing this advanced technique since 2003 in our centre, out of which more than 4500 babies have born in GFRC- MMCH till now.

      Third party reproduction includes “egg donation” and “surrogacy”. Egg donation is indicated for older women of more than 40 years, who have nonfunctioning ovaries or no ovaries due to surgery, disease or congenital cause. In surrogacy the rented mother should be less than 35 years with good uterus. This modality is considered for women who have no uterus by birth or uterus operated/removed and for women who are medically unfit to withstand a pregnancy. Since 1997, egg donation and surrogacy are being done with reasonable success rates in our institution (GFRC - MMCH).

       Cryopreservation is a modality in which embryos, sperms and eggs are being preserved by us for many months / years, which may help the needy couples to undergo almost cost free embryo transfers in subsequent cycles.

    It has been proved scientifically and socially by various genetic and clinical studies worldwide, in the past 35 years, that the children born out of ART – as test tube babies - are not different from the children born naturally. The incidences of birth defects are also at par with the naturally conceived babies. 

Dr.Nirmala Sadasivam, Leading Infertility Specialist in India

     Latest advancements in this field of Reproductive medicine introduced recently in our centre (GFRC – MMCH) includes - IMSI- Intracytoplasmic Morphologically selected Sperm Injection, Oocyte Vitrification, In Vitro Maturation of oocyes and transfer of Cytoplasm from an young women’s eggs to older women’s, bringing  exceptionally bright scope in managing the deprived infertile couples.  

To Get Pregnant via "ART – Assisted Reproduction Techniques" 

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