Tuesday, April 29, 2014

Test Tube Babies - Novel Solution For Infertility

Test Tube Babies - Novel Solution For Infertility
Test Tube Babies - Novel Solution For Infertility



All scientific Discoveries, inventions and achievements invariably lead to the betterment of human race. Test tube baby, a phenomenon of the 20th century, is also an invention of the human intellect. There are thousands of couples of in the world who are not blessed with a child. Medical researchers, after protracted attempts of many decades, have finally arrived at a solution called – test tube baby.  According to Dr.Nirmala Sadasivam, 1 in 5 couples encounter difficulty in conceiving a child. WHO has declared that 15% of the world population is facing infertility.

 GFRC is an extremely distinguished medical centre for Infertility with all facilities under one roof. It has come a long way since its inception as a pioneering institute in ERODE, Tamil Nadu since 1996. It has taken giant steps to become a center of excellence in all facets of infertility and IVF treatment options, which are offered at affordable cost for the public. This center has been a leader in Blastocyst Culture, an extended embryo Culture Technology and other novel Male Infertilitytreatment modalities like Surgical Sperm Retrievals - TESA, MESA, PESA, TESE, etc., with ICSI facility and genetic studies too. This research center is a unit of Maaruthi Medical Center and Hospitals, which is a well known 300 bed corporate hospital situated in the centre of Erode city.

The success story of GFRC & MMCH in infertility treatment is largely due to the support of an extremely dedicated and experienced IVF team led by Dr.Nirmala Sadasivam, who has invaluable experience due to trainings she had at various world class institutes overseas, since 1991, and has pioneered in Blastocyst Culture technique since 1998. She was recognized by National Academy of Medical science and offered MNAMS - membership. With the vast knowledge and experience in Blastocyst culture technique she has utilized the data of more than 4000 infertile couples treated in her centre, she could do PhD in the same specialty. This institution was endorsed in its nascent stage at the National "Art" Registry of India, and is now a prestigious senior member of ISAR, India. Another feather in their cap is the inclusion of the centre as one among the esteem early participants at ASPIRE - Asia Pacific Initiation of Reproductive Endocrinology, in their academic events. This institute is accredited to ICMR through the Indian Society for Assisted Reproduction. 
 
Dr.Nirmala Sadasivam
Dr.Nirmala Sadasivam
Dr.Nirmala Sadasivam received training in National University Hospital of Singapore which maintains a high degree of reputation and experience in implementing ART techniques. 
The world level recognition for this centre came largely due to the "Medical Miracle" where 64 year old Mrs. Pappathi Subramaniam gave birth to a healthy male baby which was flashed in all Medias worldwide. This news has gained importance and it is occupying a page in BBC web site till today. This enduring success has a strong base of stupendous extended embryo culture technology (Blastocyst Technology) which conquered all obstacles of implantation in this old woman. This scientific development was also noted in the international medical circles on account of wide coverage given by the BBC. After that many women have delivered of test tube babies after their fifties, safely with the most modern technology called “BLASTOCYST CULTURE”.

The eldest parents of universe Mr. Subramaniam (74 yrs) & Mrs. Pappathy (64 yrs)
The eldest parents of universe Mr. Subramaniam (74 yrs) & Mrs. Pappathy (64 yrs)

The first test tube baby in the district of Erode was born in this hospital in 1997. In the initial stage, only three incubators were functional, now, in 2013, the numbers of incubators were increased to twelve. This has facilitated extensive embryological work and research with complete infertility management under one roof. The latest addition to the IVF lab is called K-System-G185, the most modern device with trigas facility having the capacity of serving more number of couples (40) every day.  As many as 4800 ART cycles have been carried out in this hospital so far and close to 2700 live births have happened as a result of IVF treatment (Test Tube baby).

By following the latest strategy of Vaginal Culture, a 59 year old woman got conceived in March 2013, and delivered on 28th November in MMCH, which was the first of its kind in INDIA. This is the simplest and the most economical method of doing test tube babies without using modern incubators, thereby avoiding high expenditures.

According to the doctor, infertility in women is caused by lifestyle changes which are of primary importance. Besides, air pollution and environmental degradation also contribute to a high level. Dr. Nirmala is of the opinion that residues from the river also produce a devastating effect on the health of women folks in villages and rural areas which play havoc in the issue of child-bearing capability of women. In western countries and developed nations, higher level officials from health department, senior doctors, scientist, researchers and industrialists assemble periodically and discuss about the developments and their influence in society. They take decisions after deep deliberations – what to be done and what not. In India too, such situations should begin in order to thrash out problems affecting the people. Doctor feels that certain chemicals present in the industrial effluents cause lots of negative influence on the health of the people which is a matter of concern. Chemicals viz., sulphur dioxide, carbon monoxide and some other chemical compounds which are toxic in nature and other acidic constituents erode the health and normal welfare of the people. She says, this trend should be immediately arrested and checked in time in the interest of the society. 

As per doctor, obesity is the vital reason for Infertility. Extra fat have to be reduced by exercises at home or gym or by paramedical exercises like yoga, walking, strolling, running, jumping, etc. Physical workouts play a positive role in reducing chances of contracting diabetes as well as obesity. If either of the parents suffers from diabetes, there is a possibility of the children too contracting diabetes as a hereditary factor. Doctor feels, life cycle modifications will improve the health of obese - infertility patients.  She advises that women should marry before reaching 25 and should deliver the first child before 30. If there is delay in this process, there is a higher probability of birth defects in the children born. 

This hospital has started many activities and many campaigns to pass on the message of conquering infertility and safe motherhood to the people of Erode district. They conduct health education programs often to apprise the people of do’s and don'ts with respect to health profile. They conduct general medical camps and infertility camps and awareness programs, conferences and classes besides treatment. The hospital gives utmost importance to educate the public about various aspects of infertility management. 

Economically-deprived classes of people are treated here with nil fees. In this medical centre, 30% of the OP patients and IVF patients are treated free of cost as a point of corporate social responsibility for the past 18 years. This gesture on the part of the hospital speaks volumes of their philanthropic motivation and social commitment.  

As per Dr. Nirmala, patients from many places viz., USA, California, Italy, West Germany, Colombo, France, Singapore, Australia, Malaysia have visited this hospital and got their infertility problems solved with live births. NRIs also come to this hospital for treatment regularly. She feels, her Ph. D., which was obtained based on Blastocyst culture, is helping the people in a magnificent way to offer very reasonable success opportunity, and helping them economically by avoiding multiple attempts without success.

For More Details : Genesis Fertility Research Center
 

Thursday, March 20, 2014

First Capsule Test Tube Baby Of India

Latest modality of IVF treatment http://www.ivfgenesis.com/



Dr.Nirmala Sadasivam With First Capsule Test Tube Baby of India
Dr.Nirmala Sadasivam With First Capsule Test Tube Baby of India

     In Maaruthi Medical Centre and Hospitals [MMCH], Erode, the department of reproductive medicine headed by Dr.Nirmala Sadasivam had achieved a live birth of a male/female baby for 54 years old Mrs.Pangajam on 28th November 2013 , by the up-to-the-minute IVF technology called CAPSULE TEST TUBE BABY treatment method. This Novel treatment was done for her in March 2013 in Maaruthi Medical Centre and Hospital, Erode using a CAPSULE Device called INVOcell (Intra Vaginal Culture of Oocytes), a gas permeable, air-free plastic device manufactured in USA. This novel Capsule Test tube baby method was introduced in USA in 2011 and in India in 2012. First time in India, a live healthy baby has been delivered using this method.

     Dr.Nirmala Sadasivam has explained about this new test tube baby method, “First test tube baby of the universe was born in 1975 in London. In the past 38 years IVF science has seen incredible accomplishments. It started with two days embryo culture outside the body in an incubator has evolved now with the latest mode called “Blastocyst Culture” which offers the best possible success rates of 60-70%. The above said procedures incur expenditures for ovulation induction, ovum retrieval, embryo culture in incubators, culture Medias and for embryo transfer into the woman’s womb. Since most of ovum stimulating injections and the culture Medias in which the embryos are grown are imported, these procedures are expensive and unreachable to a common Indian even today.

 
Doctor with the Capsule, for Capsule Test Tube Baby
Doctor with the Capsule, for Capsule Test Tube Baby
  The exclusive advantage of the capsule IVF is that it attracts very low expenditure which is less than one third of routine  test tube baby treatment cost and this procedure needs only nominal Ovulation induction with minimum hormonal drugs and practically no incubation expenditure as both of the above only  constitute 80% of the expenditure of regular IVF procedure. This method is a boon for many women and men struggling with infertility whose access to treatment are not possible due to financial challenges, limited availability of specialized medical care and social or cultural roadblocks which prevent these hopeful parents from realizing their dream to have a baby. With the INVOcell Procedure, more and more patients can now receive safe, effective and affordable infertility treatment. The other laudable benefits are that it shares more or less the same percentage of success rate of the conventional IVF apart from making infertility therapy a more personal and comforting experience especially for the female partner.

     In this capsule IVF, eggs are retrieved from the woman and it will be mixed with the prepared sperms of the husband in the desired culture media in the prescribed manner. The prepared material will be placed inside the capsule under ideal aseptic laboratory condition by the specially trained personnel. The prepared CAPSULE containing the embryo along with the specific culture media which is going to nourish the embryo during the period of vaginal culture, is kept in the woman’s vaginal cavity as an outpatient procedure without anaesthesia. Vaginal canal has the required temperature (warmth) and ambient gaseous environment to promote the culture of the embryos. The cultured embryos are then replaced into the woman’s womb on third day which will further grow inside the womb like natural embryos with the ideal luteal support.

      Dr.Sadasivam, the chairman of MMCH has told the press “This capsule IVF was done in March 2013 in our centre using the device called “INVOCELL” manufactured by a company in USA.  From 10th April 13, the day pregnancy was confirmed the antenatal period was uneventful and both mother and child are doing very well now. This cost effective method is a boon for the poor infertile couples and they must utilize these opportunities to fulfill their intense desire of parenthood.

Head of the Indian marketing division of the manufactures has told that, “this method was introduced in 2012 in India and the first delivery happened in India, in Erode, in Maaruthi Medical Centre and Hospitals today. As we want to pass on this low cost Capsule IVF benefit to needy infertile population of India”.
Dr.Nirmala Sadasivam with Capsule Test Tube Baby Family
Dr.Nirmala Sadasivam with Capsule Test Tube Baby Family
Regarding this event Mr.Velappan, the husband of  Mrs.Pankajam( 54 years) has spoken to the press with heartfelt of joy and gratitude “We are hailing from an agriculture family from a village a called Sankagiri in Salem District. I am married since 25 years and we are taking treatment for the past 20 years in various institutes throughout Tamilnadu and nearby states also. Because of repeated failure I lost money, job and even confidence. I heard about the genuine infertility treatments offered at MMCH, Erode and I approached Dr.Nirmala Sadasivam for a baby. She has shown the right path with a very low cost treatment, and we are now with handful of joy and happiness, for which we are thankful for their medical team forever”.